Health plummer Vinson

Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, iron-deficiency anemia and esophageal webs. Most of the patients are white middle-aged women, in the fourth to seventh decade of life but the syndrome has also been described in children and adolescents. History
Dysphagia, if present in patients with Plummer-Vinson syndrome (PVS), is typically intermittent and limited to solids. It is usually felt in the throat.
Choking spells and aspiration may occur because of the proximal location of the web.
Weakness, fatigue, and dyspnea are secondary to iron deficiency anemia.
Weight loss is uncommon
Physical Examination
Manifestations of iron deficiency (with or without anemia) may be evident in those with Plummer-Vinson syndrome (PVS), including the following:
Angular cheilitis
Glossitis
Koilonychia (spoon nails)
Pallor
Splenomegaly, edentia (loss of teeth), and enlarged nodular thyroid glands are also described in a few patients with PVS
Treatment
Plummer-Vinson syndrome can be treated effectively with iron supplementation and mechanical dilation. In case of significant obstruction of the esophageal lumen by esophageal web and persistent dysphagia despite iron supplementation, rupture and dilation of the web are necessary. Since Plummer-Vinson syndrome is associated with an increased risk of squamous cell carcinoma of the pharynx and the esophagus, the patients should be followed closely.